WebDec 31, 2015 · These interactions involving the polycationic structure of CS and the anionic groups facilitate the permeability of the nanoparticles into the cytoplasmic membrane, leading to the loss of essential... Cytosine arabinoside combines a cytosine base with an arabinose sugar. It is an antimetabolic agent with the chemical name of 1β-arabinofuranosylcytosine. Certain sponges, where it was originally found, use arabinoside sugars to form a different compound (not part of DNA). Cytosine arabinoside is similar … See more Cytarabine, also known as cytosine arabinoside (ara-C), is a chemotherapy medication used to treat acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML), … See more Cytarabine is mainly used in the treatment of acute myeloid leukaemia, acute lymphocytic leukaemia (ALL) and in lymphomas, where it is the backbone of induction chemotherapy. Cytarabine also possesses antiviral activity, and it has been … See more It is also known as ara-C (arabinofuranosyl cytidine). • Cytosar-U • Tarabine PFS (Pfizer) • Depocyt (longer-lasting liposomal formulation) See more One of the unique toxicities of cytarabine is cerebellar toxicity when given in high doses, which may lead to ataxia. Cytarabine may cause See more Isolation of arabinose-containing nucleotides from the Caribbean sponge Cryptotheca crypta (now Tectitethya crypta) together with the realization that these compounds could act as DNA synthesis chain terminators led to exploration of these novel … See more • ADAP drugs page on cytarabine • BC Cancer network page on cytarabine • Chembank entry See more
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