High steacs trial

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WebNov 22, 2024 · We assessed the accuracy and clinical effectiveness of high-sensitivity cardiac troponin (hs-cTn) assays for early rule-out of non-ST-segment elevation myocardial infarction (NSTEMI) in adults presenting with acute chest pain. Methods Sixteen databases were searched to September 2024. Review methods followed published guidelines. WebNov 15, 2024 · The High-STEACS pathway identified 63.4% (1218/1920) of patients as low risk, with five missed events (four index type 1 myocardial infarction and one type 1 myocardial infarction at 30 days) for an NPV of 99.5% (95% CI 99.1% to 99.8%) and sensitivity of 98.0% (95% CI 96.4% to 99.5%).

High-sensitivity Troponin in the Evaluation of patients …

WebA high-sensitivity troponin assay (hs-TnI) (ARCHITECT stat; Abbott Laboratories, USA) was used to guide clinical decisions This particular assay has a 99th centile upper reference limit of 34 ng/L in men and 16 … WebThe High-STEACS trial makes use of several routine electronic health-care data sources that are linked, de-identified, and held in DataLoch Safe Haven, which is accessible by approved individuals who have undertaken the necessary governance training. Summary aggregate level data and analysis code for this study can be made available upon ... fn1335 cl-p064-al12sw-a

High Stakes Testing - Skidmore College

WebOct 15, 2024 · This study is a prespecified secondary analysis of the High-STEACS (High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome) trial, which evaluated the impact of incorporating hs-TnI in the evaluation of patients suspected of ACS on outcomes. A total of 48,282 consecutive patients (47% women) with ... WebThe High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome (High-STEACS) trial, 61 which contributed multiple diagnostic accuracy data sets, was a stepped-wedge cluster RCT that evaluated implementation of an early rule-out pathway in hospitals in Scotland. WebAug 4, 2016 · The ongoing High-Sensitivity Troponin in the Evaluation of Patients with Acute Coronary Syndrome (High-STEACS) trial 31 is investigating the clinical implications of a high-sensitivity... fn1200-w

What is High-Stakes Testing? (with pictures) - WiseGEEK

Sex-Speciﬁc Thresholds of High-Sensitivity Troponin in ACS …

WebOct 7, 2024 · High-STEACS (High-Sensitivity Troponin in the Evaluation of Patients With Suspected Acute Coronary Syndrome) is a stepped-wedge cluster randomized, controlled … WebJan 21, 2024 · The Universal Definition of Myocardial Infarction recommends high-sensitivity cardiac troponin testing and classification of patients with myocardial injury … green soapstone countertops colorsWebAug 28, 2024 · The High-STEACS trial makes use of several routine electronic health care data sources that are linked, de-identified, and held in our national safe haven, which is … green soccer ball picture

"WebOct 14, 2024 · The High-STEACS trial presented an opportunity to explore whether improved diagnostic testing—by transitioning from a conventional to a high-sensitivity cardiac troponin I test, using sex-specific thresholds, and applying the recommendations of the universal definition of MI—had differential impacts on the evaluation, treatment, and outcomes of … " - High steacs trial

High steacs trial

WebTrial Start Date: 10 June 2013 Trial Finish Date: 02 March 2024 Trial Report Date: 02 September 2024 Correspondence Address and Main Centre: Professor Nicholas L Mills Room SU225, Chancellor's Building, University of Edinburgh, Royal Infirmary, Little France, Edinburgh, EH16 4SB, UK. WebNov 7, 2024 · Biological Science Troponin Diagnosing myocardial infarction in the era of high-sensitivity troponin: the High-STEACS trial Cardiovascular Research License CC BY 4.0 Authors: Atul Anand...

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Web"High-stakes testing" refers to tests that determine whether individual students have reached a specific level of proficiency and that are intended to be used to determine whether the … WebDec 19, 2015 · This trial is registered with ClinicalTrials.gov (number NCT01852123). Findings: In patients without myocardial infarction at presentation, troponin concentrations were less than 5 ng/L in 2311 (61%) of 3799 patients, with a negative predictive value of 99·6% (95% CI 99·3-99·8) for the primary outcome.

WebApr 17, 2024 · The High-STEACS trial was directly followed by the HiSTORIC trial, addressing similar research questions and using many of the same data sources. So we have been through the loop again which has made for a more streamlined process. WebNov 1, 2024 · High-Sensitivity Cardiac Troponin Concentrations at Presentation in Patients With ST-Segment Elevation Myocardial Infarction Acute Coronary Syndromes JAMA …

WebAug 3, 2012 · Dr. Jolly, the lead investigator of RIVAL, noted that a key aspect of the RIFLE-STEACS trial is the experience level of the operators. “The message is that it’s likely you will see a benefit with radial access in STEMI with high-volume operators who are experienced with the radial technique,” he said. “I see this as quite encouraging ... WebNov 7, 2024 · The High-STEACS trial represents a challenge to the research field and fundamentally questions the current approach to the diagnosis of myocardial infarction. …

WebAug 28, 2024 · The High-STEACS trial 5 is the first randomised trial to evaluate whether the introduction of a high-sensitivity cardiac troponin I assay with a 99th centile diagnostic threshold would reduce subsequent myocardial infarction or cardiovascular death at one year in patients with suspected acute coronary syndrome.

WebNov 21, 2024 · High-sensitivity cardiac troponin (hs-cTn) assays facilitate the ruling-out of myocardial infarction (MI) but identify a high number of patients with elevated troponin … fn119459 eservice.ice.govWebMay 13, 2013 · In ten secondary and tertiary care hospitals across Scotland, the investigators will undertake a stepped wedge cluster randomized controlled trial of the … fn17 business centerWebA high-stakes test is a test with important consequences for the test taker. Passing has important benefits, such as a high school diploma, a scholarship, or a license to practice a … green soccer field backgroundWebAug 28, 2024 · High-STEACS was conducted at ten Scottish hospitals where 48,282 consecutive patients (61 years old on average, 47% women) arrived at the emergency department with suspected ACS. Individuals... fn 15 20 inch barrelWebAug 25, 2024 · The High-STEACS (High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome) pathway missed <1 in every 400 patients tested and did … fn 15® tactical .300 blk iiWebJul 11, 2024 · Trial Protocol and Statistical Analysis Plan Supplement 2. eMethods. eTable 1. Characteristics of the Study Population According to Adjudicated Diagnosis (Type 1 … fn1242aWebJan 14, 2016 · The High-STEACS trial investigators conducted a prospective cohort study of 6,304 consecutively enrolled patients with suspected acute coronary syndrome presenting to four secondary and tertiary care hospitals in Scotland. They measured plasma troponin concentrations at presentation using a high-sensitivity cardiac troponin I assay. green soccer penny