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WebJ. Med. Chem. University of Ferrara, Italy Coumarin-based human mitochondrial RNA polymerase inhibitor POLRMT: Mitochondrial gene expression, Oxidative Phosphorylation SBDD-based optimization of first-in-class POLMRMTi IMT1B (PK-focused) IMT1B/D26 A2780 IC 50 = 138/68 nM, D26 Mitoch Transc ND1 = 15% (at 500 nM) D26 MDA-MB-468, … WebISSN (print): 1756-8919 ISSN (online): 1756-8927. Frequency: 24 issues per year. Impact Factor: 4.767 (2024) Future Medicinal Chemistry welcomes unsolicited article proposals. Email us today to discuss the suitability of your research and our options for authors, including our Accelerated Publication and Open Access services. WebProfile Highlights - Ph.D. in medicinal chemistry with experience in chemistry, biochemistry, and microbiology techniques. - Technical management experience in research and development,... josh brueckner net worth