WebIt was Patricia J. et al. who raised the suspicion of association of hyponatremia with central pontine myelinolysis in 1977 2 and finally, four years later, rapid correction of … WebMay 5, 2024 · Objectives Central pontine myelinolysis (CPM) is a neurological disorder characterized by damage to the myelin and oligodendrocytes in the pons. This review focuses on the history of CPM and the discovery of its association with the treatment of hyponatremia. Methods The author reviewed original publications regarding CPM, …
Central pontine myelinolysis - Mayo Clinic Proceedings
WebIt was Patricia J. et al. who raised the suspicion of association of hyponatremia with central pontine myelinolysis in 1977 2 and finally, four years later, rapid correction of hyponatremia was found to be the cause of central pontine myelinolysis (CPM) in rats. 3 WebCentral pontine myelinolysis (CPM), a neurologic disorder caused most frequently by rapid correction of hyponatremia, is characterized by demyelination that affects the central portion of the base of the pons. There are no inflammatory changes, and blood vessels are normal. Clinical features usually reflect damage to the descending motor tracts and … fanatic\u0027s t6
Myelinolysis after correction of hyponatremia - PubMed
WebFeb 20, 2014 · Extrapontine myelinolysis in children is rare compared to adults. The most common underlying pathophysiology is rapid correction of hyponatremia. Only 2 cases were published after diabetic ketoacidosis without electrolyte imbalance in the English literature. This study presents an unusual and possibly the youngest case of extrapontine ... WebTel +81-45 787 2800. Email [email protected]. Abstract: Central pontine myelinolysis (CPM) is a rare demyelinating condition which has been reported to occur in a variety of clinical settings, but most commonly in association with a rapid rise in plasma osmolality during correction of chronic hyponatremia. WebA growing body of experimental and clinical evidence indicates that pontine and extrapontine myelinolysis is a consequence of rapid correction of hyponatremia rather than hyponatremia itself. 1 2 ... cordyline terminalis miss andrea